Mario A. Bianchet
Assistant Professor
Johns Hopkins School of Medicine
USA
Biography
Mario A Bianchet received his Ph.D. from The University of La Plata, Argentine, and performed Postdoctoral studies at Johns Hopkins School of Medicine, where he is now an Assistant Professor of Neurology since 2011. He has published 70 papers in reputed journals. As structural enzymologist and expert in ligand recognition, he has participated in several seminal structural and mechanistic studies of macromolecules and ligand/macromolecule interactions of biomedical interest. He has significant contributions to different fields, including bioenergetics: F1-ATPase, xenobiotic-response: NADPH:Quinone oxidoreductases, DNA-repair: Uracyl-Glycosylase/inhibitors, carbohydrate-recognition: animal lectins, and late-stage cell-wall biosynthesis: LD-transpeptidases and their complexes with substrates and carbapenems.
Research Interest
My research aims to understand essential relations between macromolecules’ structure and their mechanisms of action in biological processes involved in human diseases. With that goal I am applying diverse techniques and methods including x-ray scattering and diffraction, as well as computer modeling and simulation to elucidate these relations that will have a direct impact on the understanding, diagnosis, treatment and prevention of human diseases