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11th World Congress and Exhibition on Antibiotics and Antibiotic Resistance, will be organized around the theme “Use antibiotic wisely-Prevent antimicrobial resistance ”
Antibiotics 2024 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Antibiotics 2024
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Antibiotics are a type of antimicrobials that are used in treatment and prevention of bacterial infections. They may kill or inhibit the growth of bacteria. Many antibiotics are also effective against protozoans and fungi; some are toxic to humans and animals also, even when given in therapeutic dosage. Antibiotics are not effective against viruses such as common cold or influenza, and may be harmful when taken inappropriately. Physicians must ensure the patient has a bacterial infection before prescribing antibiotics.
- Introduction to antibiotic uses and challenges
- Basic principles of prescribing antibiotics
- Mechanisms of bacteriostatic or bactericidal action
- Antibiotic Use Linked to Type 1 Diabetes Diagnosis
Antibiotic resistance is a growing concern in the field of medicine and public health. It refers to the ability of bacteria to survive and grow in the presence of antibiotics that were originally effective in killing or inhibiting their growth. The mechanism and evolution of antibiotic resistance is a complex process that involves genetic changes in bacteria over time. The evolution of antibiotic resistance is driven by the selective pressure imposed by the use of antibiotics. When antibiotics are introduced into an ecosystem, they kill susceptible bacteria, but some bacteria may possess resistance genes that allow them to survive and reproduce. These resistant bacteria then have a selective advantage over susceptible bacteria, leading to the proliferation of antibiotic-resistant strains. Additionally, the misuse and overuse of antibiotics in both human and animal populations contribute to the rapid evolution of resistance. The constant evolution of antibiotic resistance poses a significant threat to human health, as it limits the effectiveness of antibiotics in treating infections. It is crucial for healthcare providers to adopt responsible antibiotic prescribing practices and for researchers to develop new antibiotics and alternative treatment strategies to combat this growing problem.
Antibiotic-resistant bacterial infections are a serious and growing global health concern. These infections occur when bacteria become resistant to the drugs that were originally designed to kill or inhibit their growth. As a result, the effectiveness of antibiotics in treating these infections is greatly reduced, leading to prolonged illness, increased healthcare costs, and higher mortality rates. There are several factors contributing to the rise of antibiotic-resistant bacterial infections. The misuse and overuse of antibiotics, both in healthcare settings and in agriculture, play a significant role. When antibiotics are used unnecessarily or inappropriately, bacteria have more opportunities to develop resistance. Additionally, the spread of resistant bacteria between individuals and healthcare facilities can occur, further exacerbating the problem. Common infections such as urinary tract infections, pneumonia, and bloodstream infections are increasingly becoming more difficult to treat due to antibiotic resistance. In some cases, there may be limited or no effective treatment options available, leading to increased morbidity and mortality rates.
Microorganisms have long been recognized as a valuable source of antibiotics. Many bacteria and fungi have the ability to produce compounds that inhibit the growth of other microorganisms, providing them with a competitive advantage in their environment. These antibiotic-producing microorganisms have played a crucial role in the development of antibiotics that are used to treat bacterial infections in humans. Bacteria such as Streptomyces and Bacillus, as well as fungi like Penicillium and Aspergillus, are well-known producers of antibiotics. These microorganisms have the genetic machinery to synthesize complex molecules with antimicrobial properties. Through a process of biosynthesis, they produce and release these antibiotics into their surroundings.The discovery and isolation of antibiotic-producing microorganisms has been essential in the development of new antibiotics. Scientists have been able to study the chemical structures and mechanisms of action of these natural compounds, leading to the synthesis of modified or more potent versions of antibiotics.
An antimicrobial therapy kills or inhibits the growth of microorganisms such as bacteria, fungi, or protozoans. Antimicrobial agents are some of the most widely, and often used therapeutic drugs worldwide. It contributes significantly to the quality of life of many people and reduces the morbidity and mortality due to infectious disease. The remarkable success of antimicrobial therapy has been achieved with comparatively little toxicity and expense.
Alternatives to antibiotics are broadly defined as any substance that can be substituted for therapeutic drugs that are increasingly becoming ineffective against pathogenic bacteria due to antimicrobial resistance. Although antibiotics remain an essential tool for treating animal diseases on the farm, the availability of effective medical interventions to prevent and control animal diseases is one of the most significant challenges facing veterinary medicine in the 21st century. Phytochemicals as antibiotic alternatives to promote growth and enhance host health. Innovative drugs, chemicals, and enzymes within the animal production chain. Vaccines as alternatives to antibiotics for food producing animals. Also recent research provides numerous possibilities for the application nanomaterials in broad-spectrum eradication of pathogenic bacteria with many applications such as skin pathogen infection, implant sterilization, and wastewater treatment.
As research into antibiotic resistance expands, it is important to adopt an explicitly proactive approach to antibiotic resistance identification and surveillance, as well as antibiotic therapy development. This proactive approach involves using a combination of functional metagenomics, next-generation sequencing and cutting-edge computational methods to monitor the evolution and dissemination of resistance before a given resistance determinant emerges in a pathogen or in the clinical setting, as well as proactively developing next-generation therapies that target these resistance determinants. Recent advances in the field highlight the promise that the next generation of resistome studies hold for characterizing and countering emerging resistance threats.
Antibiotic overuse and misuse has led to a growing number of bacteria in humans, animals and the environment that are resistant to life-saving antimicrobial therapies. Urgent action is needed to halt the development of resistance, and to accelerate new treatments for bacterial infection. Research includes epidemiology of both Gram-negative and Gram-positive infections, genetic mechanisms of resistance, evolution and transmission in the hospital setting, as well as the community, and antimicrobial stewardship
New antibiotics and non-antibiotic approaches are crucial in the fight against antibiotic resistance, a global health threat. Antibiotic resistance occurs when bacteria evolve and become resistant to the drugs designed to kill them. This makes it harder to treat infections and increases the risk of severe complications. The development of new antibiotics is essential to combat resistant bacteria. Scientists are constantly searching for novel molecules and compounds that can effectively target and kill bacteria. These new antibiotics aim to bypass existing resistance mechanisms and provide alternative treatment options. In addition to new antibiotics, non-antibiotic approaches are being explored to tackle bacterial infections. One such approach is the use of bacteriophages, which are viruses that infect and kill bacteria. Bacteriophage therapy shows promise in targeting specific bacterial strains and reducing the risk of resistance. Other non-antibiotic approaches include immunotherapy, which enhances the body's immune response to fight infections, and the use of antimicrobial peptides, which are naturally occurring molecules that can kill bacteria. Combining these new antibiotics and non-antibiotic approaches with responsible antibiotic use and infection prevention measures can help mitigate the spread of antibiotic resistance. It is crucial to invest in research and development to discover and implement these innovative strategies to ensure effective treatment options for bacterial infections in the future.
Modern antibiotics have revolutionized the field of medicine, providing effective treatment options for various diseases and infections. These powerful drugs target and kill bacteria, helping to alleviate symptoms and prevent complications. For common bacterial infections such as urinary tract infections, respiratory infections, and skin infections, antibiotics like penicillin, cephalosporin’s, and macrolides are often prescribed. These antibiotics work by interfering with the bacteria's ability to grow and reproduce, ultimately leading to their destruction. In recent years, there have been notable advancements in antibiotic development, including the introduction of broad-spectrum antibiotics that can target a wide range of bacteria. Fluoroquinolones and carbapenems are examples of such antibiotics, often used to treat severe infections caused by multidrug-resistant bacteria. Furthermore, antibiotics like tetracyclines and sulfonamides are commonly used to treat acne and other skin conditions caused by bacteria. These antibiotics work by reducing the number of bacteria on the skin and reducing inflammation. It is important to note that antibiotics are only effective against bacterial infections and should not be used to treat viral infections such as the common cold or flu. Misuse and overuse of antibiotics can contribute to antibiotic resistance, making it more difficult to treat bacterial infections in the future.