Antibiotics and Antibiotic Resistance

Mechanism of Action of Antibiotics

Antibiotic drug-target associations, and their individual direct impacts, are are generally well-characterized. Interestingly, the bacterial reactions to antibiotic medicines that add to cell death are not too comprehended and have ended up being very complex, including various hereditary and biochemical pathways. Here, we will discuss the multi-layered impacts of drug target interactions, including the fundamental cell forms repressed by bactericidal antibiotics and the related cellular response mechanisms that add to killing by bactericidal antibiotics. We also discuss new  insights into these mechanisms that have been uncovered through the investigation of biological networks, and portray how these insights together with related advancements in synthetic biology, might be exploited to make novel antibacterial treatments.